The U.S. Food and Drug Administration (FDA) approved to market Aczone (dapsone) Gel, 5 per cent for acne vulgaris topical treatment. But patients who have the enzyme deficiency, G6PD (Glucose 6-phosphate dehydrogenase), will need to be monitored with regular blood counts to detect if they are predisposed to one type of anemia (hemolytic anemia).Aczone, a trademark of QLT USA Inc., is an aqueous topical gel which contains 5 per cent dapsone. According to scientific research, combining dapsone in a Solvent Microparticulate (SMP) gel enables dapsone to be applied topically and safely. This product achieved significant per cent reduction in the number of acne lesions and better success rate on the Global Acne Assessment Score in two randomized double-blind, vehicle controlled clinical studies in 3000 acne patients.Oiliness/peeling, dryness, and erythema were the most common adverse events reported from controlled clinical trials. However, there were no significant differences in the adverse event rates between Aczone Gel and vehicle control treated patients.1.4 per cent of about 3500 patients had the enzyme deficiency -in the Aczone clinical trial program- which is consistent with the incidence in the general North American population.The company QLT will undertake a post-approval Phase IV study in 50 acne patients who have G6PD deficiency and follow them for 6 months, after which QLT expects to submit an application to the FDA to re-evaluate the Aczone label.The President and Chief Executive Officer of QLT Inc., Paul Hastings, stated that Aczone represents an important clinical advance in dermatology, has demonstrated safety and efficacy in over 4,000 patients. We are very pleased with the FDA's decision and confident in Aczone's potential as a new class of treatment for acne patients.
Over the counter and prescription acne treatments often contain chemicals that many people do not wish to use. Instead, these people search for home treatments for acne. There are many home treatments for acne that actually do work. Here are some things you can try.1. Apply essential oils, such as Tea Tree Oil, Bergamot Oil, Clove Oil, Lavender Oil, and Rosewood Oil. For sensitive skin, dilute the oil with grapeseed oil. Apply the oil before going to bed at night, then wash it away in the morning with a pure soap, such as Ivory, and clean water.2. If you are not taking any medications that could cause you to be overly sensitive to the sun, try getting some sunshine everyday. The purpose is not to tan to hide the acne. Instead, the sun actually kills the bacteria, and dries up the sebum oil that produces acne. This is a common home treatment for acne that doesn't cost anything.3. Acne begins on the inside of the body, not on the surface of the skin. Drink plenty of water - at least eight glasses per day - to help detoxify your body and cure acne. Also eat plenty of fresh fruits and vegetables.4. For home treatment for acne, apply an oatmeal mask at least once or twice a week. Cook oatmeal, and while it is still warm (not scalding hot) apply it to your entire face. Allow the oatmeal to dry, then wash it away. You can also use dried oatmeal, dampened - but not cooked - with warm water as a facial scrub to exfolliate the skin and clean the pores.5. Avoid eating processed foods, and stick to more natural fruits and vegetables. No food has ever been scientifically proven to cause acne, however, if you have a food allergy, the allergy often results in acne. Many people have food allergies, and go their entire lives without knowing it. Don't assume that a food allergy will leave you unconscious on the floor - the allergic reaction can appear in many forms, like acne breakouts. You can visit an allergist for a simple blood test to find out if you have any food allergies.There are many other home treatments for acne, some of which work, and some of which do not work. The important thing is to drink plenty of water, eat fresh fruits and vegetables, get plenty of sleep, wash your face at least twice a day, and take vitamins - especially vitamin A and vitamin E.
Having acne can be a miserable experience to have to endure. It can be physically and emotionally painful and embarrassing. It can cause feelings of isolation, low-self esteem, even depression. Acne affects nearly everyone at some point in his or her life, whether it's during puberty, pregnancy (or during some other hormonally-charged period in life), or just during any time of adulthood. But there are ways to prevent and even control acne if you take a preemptive approach. The best way to counteract the effects of this skin problem is to carry out a proactive acne treatment, which will help you to take care of your body as well as your skin.Proactive is defined as acting in advance of an expected problem, or to be anticipatory. If you know that you are prone to acne, anticipating the problem and taking steps to defend yourself against it is the best way to go. There are several proactive acne treatment measures that a person can take in order to reduce the amount of breakouts, and to keep the breakouts that do occur from being too bad. One of the best ways to deal with acne is through exercise.Exercise is not only a great way to regulate your weight and keep your body in good physical condition, but it also helps to lower stress levels that can cause or aggravate acne. In addition, sweating is a way of cleaning out the body, ridding it of oils and bad bacteria. It is important, though, to wear lightweight, breathable fabrics when exercising. Perspiration that is trapped between fabric and the skin can let bacteria grow and clog the pores, which will lead to acne.Another effective proactive acne treatment is through diet. Though it is commonly understood now that what you eat does not cause acne, it is also commonly known that certain vitamins and minerals help the body fight the war on acne. It is a good idea to eat a healthy, well-balanced diet rich in vitamins and minerals such as vitamins A, B, C, and E. This will not only give you a healthy body, but will help to curb breakouts. In addition, drinking plenty of water will help keep your skin looking fresh, and your color bright.Stress has an immense effect on a person's complexion. We wear our problems on our faces, in the form of dark circles, wrinkles, and yes, even acne. There are a variety of stressors that affect us in different ways. Stressors are things that cause anxiety to your body and your well-being, which can also cause or aggravate an acne problem. Certain external stressors involve things that negatively affect the outside of your body, and include such things as oil-ridden cosmetics, overexposure to the sun, and a poor diet. Internal stressors include factors that cause anxiety, depression, or low self esteem. Not dealing with emotions or high stress levels can cause acne flare-ups or other outward indications of inward problems. As mentioned before, exercise is an ideal way to manage stress. Also, participating in activities that you enjoy can also reduce your stress levels. And, don't forget to get an abundance of sleep if at all possible. Sleep provides your mind and body time to rest and rejuvenate.There are several acne treatments that you can perform that, if done on a regular basis, prove to be highly effective, proactive measures. For example, always try to use oil-free cosmetics that won't clog your pores. Shaving the skin with a light touch and a sharp razor or even an electric shaver helps to exfoliate the skin and won't be too rough on skin that is broken out. It is best, though to avoid areas of the skin that are especially irritated or infected, and allow them time to heal. Also, make sure to gently wash your face twice daily with lightly exfoliating products. Do not ever scrub the skin, for this can lead to further irritation and more acne problems.Taking the proactive approach to acne treatment is by far the best way to avoid embarrassing or painful breakouts. And you will find in doing so, that you will not only have healthier looking skin, but that your body and general well-being will be healthier in the effort as well.
What causes this condition that seems to chip away at the very foundations of self esteem with an almost malevolent intent? The myth is that once teenagers cross the threshold from adolescence into adulthood, the anguish caused by acne will be permanently left behind. The reality is that there is no guarantee that adulthood will offer the safe, acne-free haven that so many teens long for. Statistics indicate that 25% of the male population is plagued at some point by adult acne, while 50% of females will similarly find themselves contending with the condition as adults. It seems that no one is exempt. Infant acne can appear on the faces babies who are only three or four weeks old, or even on the faces of newborns. Since so many are afflicted - adult and child alike - there's an obvious need for real information on acne skin care that cuts through all the myths and separates fact from fiction. Lets begin at the beginning.Sebum is the natural oil produced by the skin's sebaceous glands. For reasons that aren't fully understood, the pores of the skin can become plugged with sebum, and once plugged, bacteria and dead cells can become trapped in the pores, resulting in the lesions common to acne. Acne can be defined as a condition describing blocked skin pores that result in lesions.The most common lesions are called comedones. There are two basic varieties of comedones: white heads and black heads. A white head is an occluded pore that has begun to bulge outward from the skin due to dead skin cells, bacteria, and other contaminants that have become trapped inside. This bulging dome shape often assumes a white appearance. Black heads are simply comedones that have opened, exposing the dark follicle mass inside. Acne comedones are often referred to colloquially as "zits" or "pimples."Microcomedones are a less common form of acne lesion, sometimes referred to as papules. These are basically small comedones that form from localized cellular reactions to the processes that cause acne. They usually occur in clusters and are sometimes too small to see. They can be felt as a series of little bumps along the skin surface.In more severe forms of acne, cysts, pustules and nodules and can form. A pustule is like a normal comedone, but larger due to a higher amount of dead white cells, or pus, trapped inside the plugged sebaceous follicle.Nodules are a more severe form of papules, extending deeper into the skin tissue and resulting in large raised legions that are usually inflamed and painful to touch. Finally, cysts are very large fluid filled sacs that can result from pustules or nodules. Though none of these forms of acne are dangerous or life threatening, they can leave scars and are sometimes very disfiguring.What causes acne? This is a question that scientists and doctors still havent been able to completely agree upon. Today, most theories seem to point to a combination of factors that include genetics, hormone changes, and stress. For years it was thought that diet was a strong component to acne, but most evidence today suggests that hormones and stress are more likely to be the culprits.Almost everyone will have some form of acne in their lives. Most people suffer from outbreaks of acne during their teenage years. These outbreaks are associated with hormone changes that occur during puberty. It is equally common to men and women, and usually outbreaks appear on the face. However, acne can strike at any stage in adult life, and outbreaks can appear not only on the face, but on the back, neck, arms and legs. The good news is that the situation regarding acne and "acne skin care" is by no means hopeless. Acne treatment exists. And while it might not be realistic to expect some sort of magical acne cure, there are ways to effectively tackle the problem. Once you can find easy to implement acne tips and information at websites like www.acneskincareatoz.com, there's a good possibility you'll be able to minimize your breakouts or avoid them altogether.
Unfortunately, few find it, but this is only because they haven't found the right acne cure for them. Each of us is different, and our bodies function and respond to treatment differently. What works for some, may not work for others. However, there are a few proven treatments that do provide an acne cure for a large majority of acne sufferers.The best over the counter acne cure seems to be ProActiv. This is a skin care system that contains benzoyl peroxide as the active ingredient. It is an expensive treatment, but that is because it has proven to be so effective as an acne cure. ProActiv is a non-prescription topical acne treatment, with prescription strength benzoyl peroxide.Accutane, which is a prescription medication, has also proven to be quite effective as an acne cure. However, it is also expensive, and as an oral medication, there is the possibility of serious side effects. Due to the possible side effects, many choose not to take this powerful drug, even though it works well for the majority of people who use this treatment.Another acne cure seems to be retin-a. Retin-a is used to treat acne, acne scars, wrinkles, skin discoloration, and other skin disorders. It is highly effective, with few side effects. Retin-a is used as a topical treatment, and is available by prescription. However, there are other over the counter medications that contain small amounts of retin-a.The important thing to remember is that acne cures do not work overnight. Furthermore, you may need to continue acne treatment even after the acne has cleared up, or start the treatment again should you have another outbreak in the future. Discuss the need to continue treatment with your dermatologist.The three acne cures discussed above are expensive. However, they are expensive because they work. This doesn't mean that all expensive treatments work, it simply means that these three, which have been proven to work for the majority of people who have tried these treatments, are well worth the cost. Acne MythsMyth #1: Acne is caused by poor hygiene. If you believe this myth, and wash your skin hard and frequently, you can actually make your acne worse. Acne is not caused by dirt or surface skin oils. Although excess oils, dead skin and a day's accumulation of dust on the skin looks unsightly, they should not be removed by hand scrubbing. Vigorous washing and scrubbing will actually irritate the skin and make acne worse. The best approach to hygiene and acne: Gently wash your face twice a day with a mild soap, pat dry--and use an appropriate acne treatment for the acne.Myth #2: Acne is caused by diet. Extensive scientific studies have not found a connection between diet and acne. In other words, food does not cause acne. Not chocolate. Not french fries. Not pizza. Nonetheless, some people insist that certain foods affect their acne. In that case, avoid those foods. Besides, eating a balanced diet always makes sense. However, according to the scientific evidence, if acne is being treated properly, there's no need to worry about food affecting the acne.Myth #3: Acne is caused by stress. The ordinary stress of day-to-day living is not an important factor in acne. Severe stress that needs medical attention is sometimes treated with drugs that can cause acne as a side effect. If you think you may have acne related to a drug prescribed for stress or depression, you should consult your physician.Myth #4: Acne is just a cosmetic disease. Yes, acne does affect the way people look and is not otherwise a serious threat to a persons physical health. However, acne can result in permanent physical scars--plus, acne itself as well as its scars can affect the way people feel about themselves to the point of affecting their lives.Myth #5: You just have to let acne run its course. The truth is, acne can be cleared up. If the acne products you have tried havent worked, consider seeing a dermatologist. With the products available today, there is no reason why someone has to endure acne or get acne scars.